Other Ingredients: Microcrystalline cellulose, vegetarian capsule (carbohydrate gum [cellulose], purified water), vegetable grade magnesium stearate (lubricant).
More information about Vitamin K2 Contraindications: Consult a health care professional prior to use if you are taking blood thinners. Vitamin K supplementation should be used with caution in patients with liver disease, or undergoing hemodialysis. Keep out of reach of children.
1. Vos M, et al. Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. Science. 2012 Jun 8;336(6086):1306-10.
2. Vermeer C. Vitamin K: the effect on health beyond coagulation - an overview. Food Nutr Res. 2012;56. doi: 10.3402/fnr.v56i0.5329.
3. Chatrou ML, et al. Role of vitamin K-dependent proteins in the arterial vessel wall. Hamostaseologie. 2011 Nov;31(4):251-7.
4. McCann JC, et al. Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging? Am J Clin Nutr. 2009 Oct;90(4):889-907.
5. Ibarrola-Jurado N, et al. Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease. Am J Clin Nutr. 2012 Oct 3. [Epub ahead of print].
6. Schurgers LJ, et al. Vitamin k-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype. PLoS One. 2012;7(8):e43229.
7. Geleijnse JM, et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J. Nutr. 2004. 134:3100�5.
8. Nimptsch K, et al. Dietary vitamin K intake in relation to cancer incidence and mortality: results from the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg). Am J Clin Nutr. 2010 May;91(5):1348-58.
9. Schurgers LJ, et al. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007 Apr 15;109(8):3279-83.
10. Katsuyama H, et al. Usual dietary intake of fermented soybeans (natto) is associated with bone mineral density in premenopausal women. J. Nutr. Sci. Vitaminol. (Tokyo) 2002. 48:207�15.
11. Ikeda Y, et al. Intake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese Population-Based Osteoporosis Study (JPOS). J. Nutr. 2006. 136:1323�28.
12. Fujita Y, et al. Association between vitamin K intake from fermented soybeans, natto, and bone mineral density in elderly Japanese men: the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study. Osteoporos Int. 2011 Mar 11. [Epub ahead of print].
13. Cockayne S, et al. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med. 2006 Jun 26;166(12):1256-61.
14. Ford SK, et al. Vitamin K supplementation to decrease variability of International Normalized Ratio in patients on vitamin K antagonists: a literature review. Curr Opin Hematol. 2008 Sep;15(5):504-8.
15. Weijs B, et al. Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. Eur Heart J. 2011 Oct;32(20):2555-62.